The LL-37 peptide is a versatile human antimicrobial peptide (AMP) used in research for its broad-spectrum ability to kill bacteria, fungi, and viruses, while also modulating the immune system, promoting wound healing (angiogenesis, skin regeneration), and potentially fighting infections, cancer, and autoimmune conditions, acting as a bridge between innate and adaptive immunity, though its dual role in inflammation presents complexity for diseases like psoriasis or lupus.

• Antimicrobial Agent: Kills Gram-positive/negative bacteria (like MRSA), fungi (like Candida), and viruses, disrupting biofilms and showing promise against antibiotic-resistant strains.
• Wound Healing: Promotes skin repair (re-epithelialization) and new blood vessel formation (angiogenesis) in chronic wounds, burns, and diabetic ulcers.
• Immune Modulation: Recruits immune cells (neutrophils, monocytes, T cells), influences their differentiation, and bridges innate and adaptive immunity.
• Inflammation Regulator:Can have pro- or anti-inflammatory effects, recruiting immune cells and stimulating immune responses, but also potentially worsening autoimmune conditions like psoriasis or lupus when overexpressed.