Selank is a synthetic peptide used primarily for its anti-anxiety (anxiolytic) and cognitive-enhancing (nootropic) effects. It is an analog of the naturally occurring human peptide tuftsin, which is involved in immune function.
- Anxiety and Stress Reduction: It helps manage symptoms of GAD, neurasthenia, and chronic stress by modulating GABA receptors, the brain's main inhibitory neurotransmitter system. This anxiolytic effect is comparable to low-dose benzodiazepines but without the typical side effects like sedation, addiction potential, or withdrawal symptoms.
- Cognitive Enhancement: Selank is considered a nootropic, as it can improve focus, concentration, memory, and learning abilities. It increases the expression of brain-derived neurotrophic factor (BDNF), a protein vital for neuronal health and synaptic plasticity.
- Mood Improvement: By helping to regulate neurotransmitters like serotonin and dopamine, Selank can stabilize mood and reduce symptoms of depression.
- Neuroprotective Properties: Research, mostly in animal studies, suggests it can protect neurons from damage and stress, showing potential for use in age-related cognitive decline and neurodegenerative diseases.
- Immune System Support: Mimicking the natural peptide tuftsin, Selank can enhance immune function and exhibits antiviral properties by stimulating the release of interferons and IL-6 cytokines.
- Support for Other Conditions: It has been studied as a potential complementary treatment for conditions like PTSD, ADHD, and chronic fatigue syndrome.