GHRP-6 (Growth Hormone-Releasing Peptide-6) is a synthetic peptide that powerfully stimulates the pituitary gland to release growth hormone (GH), acting as a synthetic mimic of the natural hormone ghrelin by activating the ghrelin receptor. Beyond GH release, it also boosts appetite, promotes cell survival (cytoprotection), improves gut health, enhances wound healing, and influences sleep patterns, acting as a potential therapeutic for various conditions like organ failure and injuries.

Key Functions of GHRP-6:

• Growth Hormone Release: Its primary function is to trigger significant GH secretion from the pituitary, often more effectively than natural GHRH (Growth Hormone-Releasing Hormone).
• Appetite Stimulation: It increases hunger and food intake, similar to ghrelin.
• Cell Protection (Cytoprotection): It protects cells, especially heart (cardiomyocytes) and gut cells, from damage and promotes their survival and repair.
• Wound Healing: It can improve the healing of wounds, including burns and ulcers, by promoting new blood vessel formation (angiogenesis).
• Gut Health: It influences gut epithelial function and can protect against certain types of gastrointestinal injuries and multiple organ failure.
• Sleep Regulation: It can alter sleep stages, generally enhancing certain non-REM sleep stages.
• Metabolic Effects: It can influence body weight and fat mass, often working with insulin.